Puptydes BPC-157 Joint, Tissue, & Gut Restore 2 Bottles - 60 Day Supply (Subscribe & Save)

30 Capsules - One Month Supply

Excellent · 6,000+ reviews

4.8 out of 5

Repairs
Joint, Tissue, Gut
Works Fast
Owners notice results in days
Studied
Peer-reviewed in dogs

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Lauren J.
Lauren J.

My old buddy is moving like a puppy again! this really works!

Canine-Formulated
Science-Backed
Canine-Formulated
Science-Backed
Canine-Formulated
Science-Backed
Canine-Formulated
Science-Backed
Peer Reviewed Research Studied In Dogs

BPC-157 has been studied in dogs.

Researchers evaluated BPC-157 in a controlled pharmacokinetics study using beagle dogs.

6 Beagle dogs
3 Dose levels
7 days Repeat dosing
✓
Reported as well tolerated in the dogs studied

Researchers reported no visual signs of toxicity during the study.

From Research To Our Product

The research is on BPC-157.
Our lab testing is on the actual Puptydes capsule.

BPC-157 identity Confirmed
Net peptide content 0.52 mg
Elemental impurities Pass

He L, et al. Pharmacokinetics, distribution, metabolism, and excretion of body-protective compound 157 in rats and dogs. Front Pharmacol. 2022;13:1026182. PMID: 36588717.

How BPC-157 rebuilds a joint

3D render of a canine hip joint with glowing cartilage and golden repair particles on a dark navy background

Survives the stomach

Most peptides break apart in stomach acid. BPC-157 was first identified in gastric juice, stable there by nature, in what we describe as a naturally occurring, stable form, made to hold up through digestion.

Signals repair

In preclinical research, BPC-157 has been studied for its interaction with growth factor pathways at stressed tissue, supporting the body’s own repair signaling for joints and connective tissue.

Builds new supply lines

BPC-157 has been studied for its role in angiogenesis, the formation of new blood vessels that feed hard to reach tissues like cartilage and tendon, which have notoriously poor circulation.

Lays down collagen

Collagen is the structural protein joints, tendons, and ligaments are made of. In preclinical studies, BPC-157 has been researched for its relationship with fibroblast activity and organized collagen formation.

FILMED BY THEIR OWNERS

Join the owners getting their dogs back

Same dogs, same houses, a few weeks apart. No studio, no actors. Tap the faces to see each one.

BEFORE
AFTER
START PUPTYDES

Where BPC-157 goes to work

One peptide, three repair targets.

3D medical render of a canine hip joint showing cartilage 3D medical render of a canine stifle joint showing cruciate ligaments 3D medical render of intestinal villi HIP JOINT · CARTILAGE

Support where they carry their weight

BPC-157 is a peptide researchers study for its role in supporting the tissues around the joint — cartilage surfaces, the synovial lining, and the surrounding connective tissue. It’s given daily with food in a deliberately conservative 500 mcg capsule: steady support for comfort and mobility over weeks, not an overnight fix.

For the hardworking connectors

Tendons and ligaments absorb every sprint, jump, and sharp turn your dog makes. In preclinical research, BPC-157 has been studied for its role in supporting tendon and ligament tissue — the connectors that keep active dogs moving and help seniors stay steady on their feet.

It starts in the gut

BPC-157 was first identified in the gut, which is fitting: the capsule is given with food, in what we describe as a naturally occurring, stable form — made to hold up through digestion. Alongside joints and connective tissue, it supports everyday gut lining comfort.

Find your dog's dose

Drag the slider to your dog's weight. We'll show the daily dose, how long a bottle lasts, and what it costs per day.

50 lbs

About the size of a Labrador

20 lbs 75 lbs

Dosing shown follows the Puptydes label. These are general guidelines based on weight — talk to your veterinarian about your dog. Free shipping on every order.

Real People, Real Results

The Protocol

One capsule. Four steps. That's the whole protocol.

Find your dog's dose

Find your dog's dose

Find your dog's daily dose Under 20 lb — ½ capsule (250 mcg) 20–75 lb 1 capsule (500 mcg) 75 lb and over 1 capsule daily To give a half dose: twist the capsule open and mix in half the powder.

Give it with food

Give it with food

Give the capsule whole hidden in a soft treat, or twist it open and sprinkle the powder directly over kibble or wet food. The powder is unflavored and mixes cleanly. Same time every day works best.

Follow the cycle

Follow the cycle

30 days on. 7 days off. Repeat. The rest period is part of the protocol. Most owners notice a visible difference by week 2. Don't stop at day 6 and assume it isn't working.

Watch your dog change

Watch your dog change

Easier mornings. Stairs again. More trail time. Less stiffness after rest. If you don't see a meaningful difference by day 30 we refund you in full no questions asked.

The Science Behind BPC-157

One compound. Four mechanisms. Every capsule.

Repair

BPC-157 supports your dog's natural collagen synthesis pathways — the connective tissue in joints, tendons, and ligaments. It doesn't mask discomfort. It supports the repair process at the cellular level.

Absorb

Most peptides are destroyed by stomach acid, which is why they usually require injection. BPC-157 is unusual — it's one of the few peptides stable enough to survive digestion, which is what makes a real oral capsule possible in the first place. No needles, no reconstitution.

Protect

BPC-157 supports gut lining integrity through the same gastric protection mechanisms it was originally studied for. For dogs with chronic GI sensitivity or food reactions, gut support is built into every dose.

Restore

The 30 on / 7 off protocol gives your dog's body time to respond and reset. Most owners notice a visible difference by week 2 easier mornings, more willingness to move, less stiffness after rest.

The Lab Test You Can Trust

The Lab Test

Verified at ≥99% Purity

Every batch is tested by HPLC before it ships, with mass spectrometry confirming identity. The Certificate of Analysis is available on request most brands won't show you theirs.

Formulated for Dogs, Not Adapted From One

Most BPC-157 on the market is a human capsule owners split in half and hope for the best. Puptydes is dosed by body weight, in a size built for the animal taking it.

Screened for What You Can't See

Heavy metals, microbial contamination, endotoxins all tested by a third party ISO-certified lab. Not by us. By people with no reason to be generous.

Real Science Vs. Myth

What most people believe about peptides for dogs and what the research actually shows.

Oral peptides don't absorb

Most peptides degrade in stomach acid before reaching the bloodstream. BPC-157 is different a 2022 beagle study confirmed 45–51% oral bioavailability in dogs. The compound survives gastric acid and reaches the tissue.

It's just a human supplement

Most BPC-157 brands are built for humans owners split capsules and guess at doses. Puptydes is formulated specifically for dogs, dosed by weight, and anchored by canine pharmacokinetics data. Not a human product repurposed for pets.

All supplements are the same

Purity and form matter more than most brands will tell you. We use the naturally occurring acetylated form of BPC-157, verified at ≥99% purity every batch with a third-party Certificate of Analysis. Most brands don't publish theirs.

My dog is just getting old

Age-related stiffness and slowed recovery aren't inevitable. BPC-157 supports the repair pathways your dog's body already has. Most owners see a visible difference within two weeks.

What Our Customers Are saying...

Very good 4.8/5 based on 1046 verified reviews

Money-Back Guarantee

We're so confident in the quality of our product that we offer a satisfaction guarantee. If you're not completely satisfied with your purchase, simply return the item within 30 days for a full refund.

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100% Satisfaction
Fast Shipping
Easy Returns

Money-Back Guarantee

We're so confident in the quality of our product that we offer a satisfaction guarantee. If you're not completely satisfied with your purchase, simply return the item within 30 days for a full refund.

CLAIM NOW
100% Satisfaction
Fast Shipping
Easy Returns

Frequently Asked Questions

Find answers to common questions about our products, shipping, returns, and more.

What if my vet doesn't recommend giving my dog a supplement? +

If the vet says no, it's no. We built Puptydes to support your dog's recovery and mobility, but we're not a replacement for your veterinarian's judgment. Your vet knows your dog's full medical history, current conditions, and medications in a way we never will. If they have concerns, listen to them first, and only revisit the conversation once those concerns are addressed.

What is BPC-157 and how does it work? +

BPC-157 is a 15-amino acid peptide originally derived from human gastric juice. It supports the body's natural repair pathways collagen synthesis, angiogenesis, and gut lining integrity. It doesn't mask discomfort like a painkiller. It supports the underlying repair process at the cellular level.

How do i give it to my dog? +

Follow dosing instructions as seen on the bottle. If your dog won't swallow a capsule, twist it open and sprinkle the powder directly onto kibble or wet food. The powder is unflavored and mixes cleanly. Best given at the same time each day.

How much do i give based on my dogs weight? +

Under 20 lb half capsule daily. 

20 to 75 lb one capsule daily. 

Over 75 lb one capsules daily. 

Follow the 30 days on, 7 days off cycle.

How long before I see results? +

Most owners notice a visible difference by week 2 easier mornings, more willingness to move, less stiffness after rest. For dogs with chronic joint issues or post-surgical recovery, the most significant changes typically appear by week 4 to 8. If you don't see a meaningful difference by day 30 we refund you in full.

Are your products tested for quality? +

Every batch is tested by a third-party ISO-certified laboratory before it ships. Testing includes HPLC purity verification at ≥99%, mass spectrometry identity confirmation, heavy metals panel, microbial screening, and endotoxin testing. The Certificate of Analysis is available on request at support@puptydes.com

What is BPC-157 and how does it work? +

BPC-157 is a 15-amino acid peptide originally derived from human gastric juice. It supports the body's natural repair pathways collagen synthesis, angiogenesis, and gut lining integrity. It doesn't mask discomfort like a painkiller. It supports the underlying repair process at the cellular level.

How much do i give based on my dogs weight? +

Under 20 lb half capsule daily. 

20 to 75 lb one capsule daily. 

Over 75 lb one capsules daily. 

Follow the 30 days on, 7 days off cycle.

Are your products tested for quality? +

Every batch is tested by a third-party ISO-certified laboratory before it ships. Testing includes HPLC purity verification at ≥99%, mass spectrometry identity confirmation, heavy metals panel, microbial screening, and endotoxin testing. The Certificate of Analysis is available on request at support@puptydes.com